Effects of puromycin, acetoxycycloheximide and actinomycin D on protein synthesis in goldfish brain.
نویسندگان
چکیده
EXPERIMENTS in our laboratory have demonstrated that memory fixation of a shockavoidance task in the goldfish can be blocked by puromycin or acetoxycycloheximide (AXM)$ when administered within 1 hr after training, but not at later times (AGRANOFF and KLINGER, 1964; DAVIS, BRIGHT and AGRANOFF, 1965; AGRANOFF, DAVIS and BRINK, 1965, 1966). The present studies report the effects of these compounds as well as actinomycin D on the incorporation of [3H]leucine into goldfish brain protein.
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ورودعنوان ژورنال:
- Journal of neurochemistry
دوره 13 10 شماره
صفحات -
تاریخ انتشار 1966